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KMID : 1011420150200040519
Journal of Korean Ophthalmic Optics Society
2015 Volume.20 No. 4 p.519 ~ p.526
Comparison Among the Four Examination Methods for Dry Eye (OQAS test, TBUT, Schirmer Test, McMonnies test)
Park Chang-Won

Kim Hyo-Jin
Abstract
Purpose: To evaluate the changes of OSI value according to tear-film instability measured serially by OQAS(Optical Quality Analysis System, Visiometrics, Spain) every seconds. The presented study analyzed the relationship of the OQAS parameter with the results of the tear-film break-up time, Schirmer test, and the McMonies score.

Methods: 147 eyes of 82 subjects were randomly selected from university students (age: 21.51¡¾3.97, male 45, female 37). Subjects were measured tear-film break-up time, Schirmer test, McMonies score and once every second for 15 seconds after blinking by continuous measurements from OQAS system.

Results: The normal eye groups presented OSI values of 2.13¡¾1.16 while the dry eye groups had OSI values of 3.76¡¾1.42. Therefore, a significant difference between the normal eye group and dry eye group was discovered (p<0.05). In addition, the OSI value of all subjects increased over time. The OSI value, which was measured every second after blinking occurred, significantly increased between 6 seconds and 7 seconds after the start of the measurement (p<0.05). OSI cut off of 30% (sec.) showed a greater correlation; TBUT (r = 0.855, p = 0.000), McMonies test (r = ?0.351, p = 0.003), Schirmer (r = 0.316, p = 0.012).

Conclusions: Continuous measurement of OQAS showed a high correlation with the value of the existing dry eye tests. Therefore, Analysis of OSI values by utilization of OQAS could be useful in objectively evaluation of tear film in patients.
KEYWORD
OSI, Dry eye, TBUT, McMonnies test, Schirmer test
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